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<table width="100%" summary="page for rats"><tr><td>rats</td><td align="right">R Documentation</td></tr></table>

<h2>Rat treatment data from Mantel et al</h2>

<h3>Description</h3>

<p>Rat treatment data from Mantel et al.
Three rats were chosen from each of 100 litters, one of which was
treated with a drug, and then all followed for tumor incidence.
</p>


<h3>Usage</h3>

<pre>rats</pre>


<h3>Format</h3>



<table summary="Rd table">
<tr>
 <td align="left">
    litter:</td><td align="left"> litter number from 1 to 100</td>
</tr>
<tr>
 <td align="left">
    rx:</td><td align="left"> treatment,(1=drug, 0=control) </td>
</tr>
<tr>
 <td align="left">
    time:</td><td align="left"> time to tumor or last follow-up</td>
</tr>
<tr>
 <td align="left">
    status:</td><td align="left"> event status, 1=tumor and 0=censored</td>
</tr>
<tr>
 <td align="left">
    sex:</td><td align="left"> male or female
  </td>
</tr>

</table>



<h3>Note</h3>

<p>The subset of females (odd numbered litters) was used Lee et al.</p>


<h3>Source</h3>


<p>N. R. Bohidar and J. L. Ciminera.
Mantel-Haenszel analyses of litter-matched time to response data,
with modifications for recovery of interlitter information.
Cancer Research, 37:3863-3868, 1977. 5 
</p>


<h3>References</h3>


<p>E. W. Lee, L. J. Wei, and D. Amato,
Cox-type regression analysis for large number of small groups of
correlated failure time observations,
in &quot;Survival Analysis, State of the Art&quot;, Kluwer, 1992.
</p>


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